1. An overactive immune system
1. An overactive immune system
While the exact cause of your CSU is unknown, it's believed to start with the immune system getting confused by an unknown internal cause and mistakenly reacting to an internal trigger.
What is chronic hives?
Chronic spontaneous urticaria (CSU), also known as chronic hives with no known external trigger, is a condition characterized by hives, swelling, or both for more than 6 weeks.
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What to know about chronic hives
While it is natural to look for causes for your chronic hives, CSU isn’t caused by an allergy or external trigger, so what you ate, wore, or touched does not start or trigger your flares, but some may worsen symptoms. Chronic hives is thought to be linked to an overactive immune system. It is different from other forms of hives or swelling that can be triggered by external factors such as foods, cold, heat, and sweat.
Chronic hives can show up anywhere on the body. They are sometimes accompanied by swelling—also called angioedema—of the lips, eyelids, hands, feet, and other areas. Both hives and swelling can make people feel miserable and impact many aspects of their lives.
One potential cause of your CSU: an overactive immune system
One potential cause of your CSU: an overactive immune system
2. An unnecessary immune response
2. An unnecessary immune response
Like a chain reaction, the mistaken signal is passed through the immune cells.
3. Histamine release
3. Histamine release
The signal causes the cells to release a large amount of histamine.
4. The common symptoms
4. The common symptoms
The result is the common symptoms of CSU, including hives, itch, and severe swelling under the skin (angioedema).
Take a closer look at the science of CSU with the "What's Really Driving Your Chronic Hives?" guide.
Chronic hives by the numbers
*Calculated estimate.
Diagnosing chronic hives unfortunately takes time
It’s frustrating that it can sometimes take over 2 years to get a chronic hives diagnosis or treatment. If you still have questions or concerns, don't give up. Talk to your health care provider. Find out about current management approaches.
The serious physical symptoms of chronic hives
Compromise is a part of life, but it shouldn't have to be when it comes to chronic hives
Itchy hives and swelling are common symptoms of chronic hives. However, there are actions you can take to help manage your condition.
Download Understanding Chronic Hives to get key information on chronic hives, management, and getting the most out of discussions with your health care provider.
Living with chronic hives today is a challenge
The reality is that living with chronic hives goes way beyond the physical symptoms—and you’re far from alone in this experience.
CSU Fact or Fiction Quiz
Now that you’ve learned about chronic hives, uncover 6 facts about CSU and debunk some common myths about the condition.
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Access tools and tips for managing your chronic hives.